Page 100 - Zbornik_Konf_2019

https://doi.org/10.15414/2019.9788055220703

4 International Scientific Conference Abstracts Book
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ANTIMYCOTIC EFFECT OF SOME ESSENTIAL OILS ON CANDIDA CLINICAL ISOLATES

Tetiana Kohuch , Maryna Kryvtsova , Natalja Timoshok , Mykola Spivak 2
1
2
1
1 Uzhhorod National University, Uzhhorod, Ukraine; E-mail.: maryna.krivcova@gmail.com
2 D.K. Zabolotny Institute of Microbiology and Virology of NAS of Ukraine, Kyiv, Ukraine
The significance of opportunistic pathogenic bacteria in the development of
inflammatory diseases and complications is shown to be continuously growing over the past
several decades. Of them, the spread of antibiotic-resistant agents of opportunistic infections
has become a most burning problem. Under such conditions, it becomes especially important
to perform research aimed at the search for alternative anti-microbial materials. The sources
for such materials are the plants that have for a long time been used in popular and traditional
medicine. The plant-based materials, essential oils in particular, often demonstrate a high
level of direct antimicrobial activity.
The purpose of the work was to study analyze the sensitivity of the Candida clinic
isolates to essential oils and antibiotics.
For antibiotic susceptibility and antimicrobial activity testing was used disc and agar
diffusion method. The analysis of essential oils was carried out by Gas Chromatography
method.
Most of the Candida strains, even antibiotic-resistant ones, were ascertained to be
susceptible to the essential oil of Thymus vulgaris L. The essential oils of Hyssopus officinalis L.
and Rosmarinus officinalis L. were shown to be characterized by moderate antibacterial
activity. The sensitivity to Mentha piperita L. and Salvia officinalis L. was strain-specific.
By the level of antimycotic activity, the essential oils may be classified in a descending
line beginning with Thymus vulgaris showing the most expressed antimicrobial activity, down
to Hyssopus officinalis, Rosmarinus officinalis , Mentha piperita, and Salvia officinalis. The
essential oil of Matricaria recutita L. showed no antimycotic activity.
The obtained results have proved the actuality of further studies of the impact of
essential oils upon microorganisms, including those with multiple resistances to medical
antibacterial preparations.

Keywords: Сandida strains, essential oils, antibiotic-resistant microorganisms, antimycotic activity.

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September 11–13, 2019