Page 149 - Zbornik_Konf_2019

https://doi.org/10.15414/2019.9788055220703

4 International Scientific Conference Abstracts Book
th
POSSIBILITY OF USING ALIEN ADENOCAULON ADHAERESCENS MAXIM. (ASTERACEAE) AS
THE MEDICINE PLANT
Yulia Vinogradova , Anastassia Ganina , Olena Vergun
2
1
1
1 N.V. Tsitsin Main Botanical Garden of Russian Academy of Sciences, Moscow, Russian Federation;
E-mail.: gbsad@mail.ru
2 M.M. Gryshko National Botanical Garden of the National Academy of Sciences of Ukraine
Kyiv, Ukraine
The searching for new resource plant species is the main target of humanity. In this
respect, the genus Adenocaulon attracts our attention. A. adhaerescens Maxim. is the perennial
herb, distributed in Russian Far East. This species has not yet been used anywhere. On the
other hand, the aerial part of closely related A. himalaicum Edgew. has been used in China,
Korea, and Japan for treatment abscess, hemorrhage, and inflammation (Hak, Kang, 2001).
Previous chemical investigations of A. himalaicum indicated that caffeic acid derivatives were
the main components (Kulesh et al., 1986). Acetylene and a monoterpene glycoside have been
isolated (Hak, Kang, 2001) and a new tricyclic- α, β-unsaturated ketone (adenocaulone) and a
new δ-hexane lactone glycoside (adenocaulolide) have been isolated later (Wang et al., 2007).
Wang et al. (2007) employed the cup-plate method and they reported, that adenocaulolide
exhibited antibacterial activity against Escherichia coli and Staphylococcus aureus. Many
compounds active against cancer cells have also been reported. Extract originating from the
aerial part (but not from the roots) of A. himalaicum is active against human gastric
adenocarcinoma (MK-1), human uterine cancer (HeLa), mouse melanoma (B16F10) and
human T-cell lymphotropic viruses of type 2 (MT-2) (Kinjo et al., 2016).
However, according to Korean scientists, the antioxidant activity of A.himalaicum was
low: 20.2 % (methanol extracts) and 17.8 % (aqueous extracts) (Lee et al., 2011). Despite this
data, we examined aqueous and alcoholic extracts derived from different organs of A.
adhaerescens as potential antioxidants. Plants were collected in the Main Botanical Garden of
Russian Academy of Sciences. We collected separately leaves and inflorescences from 10–20
plants per each local population.
Free radical scavenging activity was measured by 2.2- diphenyl-1-picrylhydrazyl
(DPPH·) method according to Brand-Williams et al. (1995).
The total antioxidant activity of extracts from young plants collected in April 2018 was
quite high and had 79.73 % (methanol extracts), 80.37 % (ethanol extracts) and 34.40 %
(aqueous extracts). In September 2018, the total antioxidant activity of extracts from leaves
was lower and had 76.48 % (methanol extracts), 59.26 % (ethanol extracts) and 47.99 %
(aqueous extracts). The total antioxidant activity of extracts from inflorescences was higher:
83.42 % (methanol extracts), 84.90 % (ethanol extracts) and 48.84 % (aqueous extracts).
Thus, our results demonstrate a broad reaction norm of phytochemical characteristics within
the vegetation season.
Our results indicate that alien A. adhaerescens may be useful as potential antioxidant
sources for improving human antioxidant defense system. We recommend seedlings or
inflorescences of this taxon for further study.

Keywords: Adenocaulon, antioxidant activity, invasive species.
Acknowledgments
This work was carried out in accordance with the MBG RAS Research Project (118021490111-5) and
National Scholarship Programme of the Slovak Republic.

4 International Scientific Conference Agrobiodiversity Nutrition, Health and Quality of Human and Bees Life |149
th
September 11–13, 2019