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https://doi.org/10.15414/2019.9788055220703

            4  International Scientific Conference                                           Abstracts Book
              th
               EXPERIENCE OF RATIONAL VITAMIN SUPPLEMENTS INTAKE IN THE OBSTETRICIAN
                                                       PRACTICE
                        Anastasiia Aksonova , Iryna Ventskovskaya , Natalia Bondarenko ,
                                               1
                                                                                                1
                                                                        1
                                        Pavlo Aksonov , Olena Palamarchuk       3
                                                        2
                1 O.O. Bogomolets National medical university, Kyiv, Ukraine; E-mail.: aks.anastasiia@gmail.com
                2 State Institute of Urology of the National Academy of medical sciences of Ukraine, Kyiv, Ukraine
                       3 P.L. Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine

                  Maintaining a healthy, balanced diet during the pregnancy period is important but
            additional supplements have been shown to be important as well. Nowadays, in the literature
            discusses the position that the use of vitamin supplements  during pregnancy affects the
            increase in baby's weight, which leads to macrosomia and related maternal complications
            during the period of gestation and delivery. The question of the expediency of the
            appointment of vitamins remains debatable, which determines the relevance and aim of our
            study. The aim of this study was to evaluate the frequency of fetal macrosomia development,
            maternal gestational and intrapartum pathology  and positive impact in the case of using a
            complex of vitamins during the period of pregnancy.
                  On the basis of the Perinatal Center of Kyiv, 95 women, with singleton pregnancy who
            delivered a healthy babies during a 2019 year were divided into three groups:  1 – women
            who received vitamins during the entire period of gestation until the moment of delivery and
            additional iron in case of diagnosed anemia; 2  – women who used a balanced diet and, if
            necessary, received iron in the diagnosis of anemia and 3 (control)  – women who did not take
            vitamin supplementation with a physiological course of pregnancy and after a childbirth. For
            preventive purposes to protect the mother and the newborn from the bleeding, in order to
            form newborn coagulation factors in the liver, the mother and the baby after the birth were
            given vitamin K1 1.0 intramuscularly. It  was analyzed the general women anamnesis,
            metabolic risk factors, course of pregnancy and delivery and weight of the newborns (more
            than 4500 grams and less than 4500 grams). The statistical processing of the obtained results
            was carried out using standard methods of variation statistics.
                  Among the 95 women who were participated in the study, 27 had fetal macrosomia.  The
            fetal birth weight was significantly higher in the vitamin supplementation group (29 % versus
            6.31 %; 5.3 %, p >0.05). Among the complications of the gestational period, patients of the 1st
            group were significantly more likely, compared with the other two groups of the study, early
            toxemia, and polyhydramnios were detected (p > 0.05) and a significantly higher cases of
            labor trauma, pathological deliveries and operations – cesarean section (12 % in case of
            compare with 6 % – in the second group and 7 % – in the control group).
                  Prolonged intake of vitamin supplementation increases the risk of fetal macrosomia and
            for the mother – the frequency of induction of labor, pathological labors, injury to the birth
            canal and operative interventions. It should be clearly taken into account the feasibility of the
            appointment of vitamins for the entire duration of pregnancy and, if possible, cancellation of
            their admission after 30 weeks of gestation with replacing their reception with balanced
            rational nutrition. Vitamin K administration to the women in labor to reduce the development
            of the hemorrhagic disease of the newborn is still controversial.
            Keywords: pregnancy, nutrition, vitamin supplements, fetus, macrosomia, vitamin K.













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